方法：白内障患者40例80眼，随机分为两组。A组：非球面AcrySof ReSTOR+3D(SN6AD1)IOL植入组； B组：非球面AcrySof ReSTOR+4D(SN6AD3)IOL植入组，其中A组为实验组，B组为对照组。术后1d； 1wk； 1，3mo行常规检查，并检查术眼裸眼远(UCDVA)、中(UCIVA)、近视力(UCNVA)。术后3mo检查最佳矫正远(BCDVA)、近视力(BCNVA)，以及最佳矫正远视力下的近(DCNVA)、中视力(DCIVA)； 检查对比敏感度及波前像差； 绘制离焦曲线，并进行主观问卷调查评分。

结果：术后1d； 1wk； 1，3mo，两组的UCDVA差异均无统计学意义(P>0.05)，UCIVA的差异均有统计学意义(P<0.05)。UCNVA在术后第1d，两组间的差异有统计学意义(P<0.05)，而在其余时间段，两组间差异无统计学意义(P>0.05)。术后3mo时，两组的BCDVA，BCNVA，DCNVA，DCIVA差异均无统计学意义(P>0.05)； 两组间总像差、高阶像差、球差间，差异无统计学意义(P>0.05)； 在各个视角水平有/无眩光下，对比敏感度差异无统计学意义(P>0.05)。离焦曲线显示：B组在+0.0D和-3.0D处形成两个焦点，而A组不仅在+0.0D和-2.5D处形成两个焦点，而且在-2.0～-2.5D之间可形成一个平台期。问卷调查显示：两组患者视远、视近的满意度较高； 而视中距离时，A组患者满意度明显高于B组。两组患者术后视觉不良症状发生率，差异无统计学意义(t=-0.87，P>0.05)。

结论：非球面AcrySof ReSTOR+3D IOL植入术后，为患者提供了良好的远、中、近全程视力，尤其是中距离视力较非球面AcrySof ReSTOR+4D IOL有了显著的改善，且没有明显的视觉干扰，提高了患者的视觉和生活质量。

METHODS: Forty patients with cataract(80 eyes)were divided into two groups: Group A(20 patients, 40 eyes): implanted with AcrySof ReSTOR+3D(SN6AD1); Group B(20 patients, 40 eyes): implanted with AcrySof ReSTOR+4D(SN6AD3). Uncorrected distance visual acuity(UCDVA), uncorrected intermediate visual acuity(UCIVA), uncorrected near visual acuity(UCNVA)were observed at 1 day, 1 week, 1 month, 3 month postoperatively. BCDVA, BCNVA, DCNVA, DCIVA, aberration, contrast sensitivity were examined at 3 month postoperatively. Binocular defocus curve-a full range of vision also were examined at 3 month postoperatively.

RESULTS: All of the eyes had best UCDVA, but, group A showed statistical superiority in UCIVA at 1 day, 1 week, 1 month and 3 month(P<0.05). It showed no statistical difference in UCNVA at 1 week, 1 month and 3 month, but except 1 day after surgery. Both two groups showed no statistical difference in BCDVA, BCNVA, DCNVA, DCIVA, aberration and contrast sensitivity at 3 month postoperatively(P>0.05). Binocular defocus curve-a full range of vision showed that group A had two focuses at +0.0D and -3.0D, but, besides the two focus:+0.0D and -2.5D, group B also had a platform level from -2.0D to -2.5D. Questionnaire showed that both of two groups had no obviously visual disturbance(t=-0.87, P>0.05). But, aspherical AcrySof ReSTOR+3D IOL showed more superior vision performance in intermediate vision.

CONCLUSION: The aspherical AcrySof ReSTOR+3D IOL can provide patients with excellent outcomes in distant, intermediate and near vision. Compared with aspherical AcrySof ReSTOR+4D, it shows more superior vision performance in intermediate vision, reduces the dependence on spectacles and improves the quality-of-life.