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[摘要]
目的:研究翼状胬肉切除联合结膜瓣转移术与翼状胬肉切除联合角膜缘干细胞移植术手术前后眼前节屈光状态的改变。
方法:选取单侧翼状胬肉患者分两组,A组翼状胬肉切除联合结膜瓣转移术,B组翼状胬肉切除联合角膜缘干细胞移植术,术前测量胬肉大小、记录术后15d及1mo裸眼视力、角膜曲率。
结果:两组术后裸眼视力均有提高。角膜水平曲率:两组术后比术前都有显著提高。角膜垂直曲率:A组术后比术前有所提高; B组术后15d与术前无统计学差异,术后1mo比术前提高。角膜平均曲率:两组术后比术前提高,差异有统计学意义。
结论:翼状胬肉侵入角膜>2.5mm就可引起影响视力的角膜散光,行胬肉手术有临床意义。翼状胬肉手术使术后患者裸眼视力提高,水平径线角膜曲率回升,而垂直径线角膜曲率变化不明显。术后1mo时翼状胬肉切除联合结膜瓣转移术和翼状胬肉切除联合角膜缘干细胞移植术对角膜曲率的影响两种手术方式未见明显统计学差异。
[Key word]
[Abstract]
AIM: To study the changes of corneal curvature after the operation of pterygium excision with transplantation and pterygium excision with limbal stem cell transplantation.
METHODS:Patients with pterygium were selected. They were divided into 2 groups in random: simple pterygium excision was performed in group A; pterygium excision with limbal stem cell transplantation was performed in group B. The results of visual acuity, astigmatism, corneal curvature and central anterior chamber depth were tested between pre-surgery, post-surgery 15 day and post-surgery 1 month.
RESULTS:Visual acuity seemed to be mostly unaffected up to a height of 2.5mm. Naked visual acuity of post-surgery was better than that of pre-surgery. Corneal horizontal curvature on post-surgery was statistically and significantly improved. Corneal vertical curvature: group A, the corneal vertical curvature of post-surgery was higher than that of pre-surgery(P<0.05); 15 days postoperatively, the vertical curvature of group B had no statistical difference with that of pre-surgery(P>0.05), and 1 month postoperatively, the vertical curvature was higher than that of pre-surgery and post-surgery 15 days(P<0.05). Corneal mean curvature on post-surgery was statistically and significantly better than that of pre-surgery.
CONCLUSION: The patient's naked eye visual acuity is improved after pterygium surgery; the horizontal diameter line curvature of the cornea is ascended, but the vertical diameter line curvature of the cornea did not change significantly.
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