方法：选择2011-09/2012-09我院的常规体检者233例为研究对象(均无眼前节疾病)， 主要包括问卷调查和泪液功能检测两个部分。问卷调查内容有工作环境、吸烟情况、职业、荧光屏接触时间、驾车时间、空调房内停留时间等。先行单因素分析， 找出与干眼症发病相关的环境因素， 然后再对有意义的因素进行多因素综合分析， 找出并确定导致干眼症的主要危险因素。

结果：单因素分析结果说明： 与干眼症发病相关的环境因素有荧光屏接触时间、工作环境、吸烟情况、驾车时间、空调环境停留时间。Logistic回归分析结果表明， 有统计学意义的因素是： 荧光屏接触时间、工作环境、吸烟情况、驾车时间。

结论：就纳入本研究的因素而言， 影响干眼症发病的主要环境因素是荧光屏接触时间、工作环境、吸烟情况、驾车时间。

METHODS: Totally 233 subjects were chosen out of routine physical examining persons in our hospital from September 2011 to September 2012. There was no eye disease of anterior segment. It mainly included two parts-questionnaires and tear function tests. Questionnaire content included working environment, smoking status, occupation, the phosphor screen contact time, driving time, and air-conditioned room residence time. First, single-factor analysis was performed to identify the environmental factors associated with dry eye incidence, then the meaningful factors with multifactor comprehensive analysis was made to identify and determine the major risk factors leading to dry eye.

RESULTS:Univariate analysis showed that environmental factors associated with dry eye incidence were phosphor screen contact time, work environment, smoking status, driving time, and air-conditioned room residence time. Logistic regression analysis showed that the significant factors were the phosphor screen contact time, work environment, smoking status, driving time.

CONCLUSION:In terms of the factors included in this study, the main environmental factors impacting dry eye disease is phosphor screen contact time, the work environment, smoking status, driving time.