方法：严重非增殖期糖尿病视网膜病变患者120眼，按白内障手术时间分为三组。A组：未行全视网膜光凝； B组：全视网膜光凝≤3mo； C组：全视网膜光凝≥6mo。观察最佳矫正视力、用OCT评估术前、术后1，6mo的黄斑厚度、黄斑水肿发生率。

结果：术后6mo，三组黄斑水肿的发生率分别为10.3%，30.6%，4.4%，B组分别与A组和C组相比，黄斑水肿发生率的差异有统计学意义(χ²=4.821，10.120； P<0.05)。同时，最佳矫正视力也明显低于其他两组，差异具有统计学意义(χ²=9.924，12.101； P<0.05)。

结论：眼底光凝术后短期内施行白内障手术，有增加术后黄斑水肿的风险。

METHODS:Totally 120 eyes with severe NPDR were divided into 3 groups according to the timing of cataract surgery. Group A never treated with panretinal photocoagulation, and focal or grid macular laser. Group B was treated with panretinal photocoagulation and focal or grid macular laser for less than 3 months. Group C was treated with panretinal photocoagulation and focal or grid macular laser for more than 6 months. We examined the changes of macular thickness using OCT before cataract surgery and 1 month and 6-months after surgery. The central subfield mean thickness(CSMT)was used to evaluate macular edema which was defined as an increase of CSMT(ΔCSMT)> 30% from the baseline. We also analyzed the best-corrected visual acuity of the three groups.

RESULTS: Macular edema occurred in 4 eyes(10.3%), 11 eyes(30.6%)and 2 eyes(4.4%)from the three groups respectively. 6 months after operation, compared to the A, C groups, macular edema from the group B were significantly different(χ²=4.821, 10.120; P<0.05). The best-corrected visual acuity of the group B was lower than the other groups(χ²=9.924, 12.101; P<0.05).

CONCLUSION: After treated with panretinal photocoagulation within short-term, cataract surgery might improve the risk of postoperative macular edema.