[关键词]
[摘要]
临床上对于视网膜退行性疾病的治疗仍然只停留在改善循环、营养神经等支持治疗阶段,缺少特效的治疗方法,骨髓间充质干细胞(bone mesenchymal stem cells,BMSCs)是具有较强自我复制功能和多向分化潜能的一类细胞,人们开始通过尝试不同的分离、诱导、移植等手段,以实现其向视网膜细胞的转化,并最终实现体内的替代治疗。我们就BMSCs在视网膜移植领域的研究进展进行综述,以期为进一步的研究提供参考。
[Key word]
[Abstract]
Nowadays, treatments for retinal degenerative diseases mainly stay in supportive treatments such as improve circulation, nourishing nerve in the clinical. It still lacks effective treatment. As bone marrow mesenchymal stem cells(BMSCs)have high expansion potential and autologous immunological characteristics,people have tried various ways of isolation, induction, transplantation and so on,with a purpose to transform BMSCs to retinal nerve cells,and ultimately make cell-replaced therapy available. We reviewed the current literature for trials and case reports on retina transplantation of BMSCs, to provide help for the further research.
[中图分类号]
[基金项目]
黑龙江省教育厅科学技术研究项目(No.12521530)