优碘联合石碳酸烧灼治疗真菌性角膜溃疡的临床观察

Clinical observation of povidone iodine combined with carbolic acid in the treatment of fungal corneal ulcer

摘要:

目的：观察用优碘联合石碳酸治疗真菌性角膜溃疡的临床疗效。

方法：将临床确诊为真菌性角膜溃疡110眼随机分为两组，每组55眼。观察组：先用优碘滴眼后用石碳酸烧灼角膜溃疡再用氟康唑眼膏及重组牛碱性成纤维细胞生长因子眼胶包眼。对照组：用碘酊烧灼角膜溃疡再用氟康唑眼膏及重组牛碱性成纤维细胞生长因子眼胶包眼。观察碘酊和优碘联合石碳酸治疗真菌性角膜溃疡的临床可行性，并进行对比研究。

结果：观察组55眼用优碘联合石碳酸烧灼角膜溃疡创面所有溃疡愈合，病程缩短，效果优于对照组(P <0.05)。

结论：优碘滴眼联合石碳酸烧灼在治疗真菌性角膜溃疡中可以明显提高治愈率，是一种有效、安全的治疗方法。

Abstract:

AIM:To observe the clinical curative effect of povidone iodine combined with carbolic acid in the treatment of fungal corneal ulcer.

METHODS: A total of 110 eyes clinically diagnosed with fungous cornea ulcer were divided to two groups at random, each with 55 eyes. The observation group was firstly treated with povidone iodine eye drops, carbol cauterize corneal ulcer and then, Fluconazole eye ointment and recombinant bovine basic fibroblast growth factor gel enveloping eyes. The control group was firstly treated with iodine tincture cauterize corneal ulcer and then used Fluconazole eye ointment and recombinant bovine basic fibroblast growth factor gel enveloping eyes. The clinical feasibility of iodine tincture and povidone iodine combined with carbolic acid in the treatment of fungal corneal ulcer was observed and comparatively studied.

RESULTS: Fifty-five eyes in the observation group used povidone iodine combined with carbolic acid cauterize corneal ulcer wound surface, all ulcer healed up, and the course of disease was shortened, the effect was better than the control group(P<0.05).

CONCLUSION:Povidone iodine combined with carbolic cauterize in the treatment of fungal corneal ulcer can enhance the curative rate obviously. It is an effective and safe therapeutic method.