普拉洛芬滴眼液治疗干眼症疗效观察

Efficacy of pranoprofen eye drops in dry eyes patients

摘要:

目的：观察1g/L普拉洛芬滴眼液治疗干眼症的疗效。

方法：选择我院2011-01/12门诊诊断为干眼症的患者100例，随机分成A、B两组，A组：1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用，4次/d点眼，1滴/次。B组：1g/L玻璃酸钠滴眼液单独应用，4次/d点眼，1滴/次。试验疗程为14d。所有的患者符合入选标准，用药前及用药后14d观察患者的问卷评分、Schirmer I试验、角膜荧光素染色评分。比较两组的结果，进行统计分析。

结果：1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用治疗干眼症患者的效果明显优于单纯使用1g/L玻璃酸钠滴眼液治疗组，两组结果差异有统计学意义。

结论：1g/L普拉洛芬滴眼液治疗干眼症，对于缓解症状，改善角膜情况效果良好。

Abstract:

AIM:To observe the effect of 1g/L pranoprofen eye drops in the treatment of dry eye.

METHODS: A total of 100 dry eyes patients, from the outpatient department in our hospital between January and December of 2011, were randomly divided into two groups: group A was treated by 1g/L pranoprofen drops combined with 1g/L sodium hyaluronate eye drops, 1 drop each time, 4 times/d for each eye; group B was treated by 1g/L sodium hyaluronate eye drops alone, 1 drop each time, 4 times/d, for each eye, All patients met the inclusion criteria before treatment and were observed before and after 14 days of treatment with questionnaire scores, Schirmer Ⅰ trial, corneal fluorescein staining scores. The results of the two groups were compared for statistical analysis.

RESULTS: The effect of 1g/L pranoprofen eye drops combined 1g/L of sodium hyaluronate eye drops was significantly better than that of 1g/L of sodium hyaluronate eye drops in the treatment of dry eye patients. There was significant difference between two groups.

CONCLUSION: 1g/L pranoprofen is effective for dry eye to relieve symptoms and improve corneal situation.