中度曲率性近视与轴性近视的高阶像差比较研究

Study on higher order aberrations in moderate curvature myopia and axial myopia

摘要:

目的：针对不同类型中度近视眼高阶像差的分析，探讨中度近视眼中曲率性近视与轴性近视高阶像差的差异。

方法：采用前瞻性研究，选取单纯性中度近视眼患者39例56眼， 将其分为两组：A组为中度曲率性近视眼组(11例/16眼)，平均年龄22±2岁，平均眼轴长度23.89±0.13mm，平均角膜曲率45.56±0.95D，平均屈光度4.58±0.82D； B组为轴性近视眼组共28例40眼，平均年龄22±3岁，平均眼轴长度25.82±0.44mm，平均角膜曲率41.93±0.85D，平均屈光度4.50±0.78D。利用波前像差仪获取入选患眼瞳孔分别为4，5，6mm时高阶像差值，进行分组比较。

结果：A，B两组平均年龄与平均屈光度比较，差异无显著性(P>0.05)； 两组平均角膜曲率与平均眼轴长比较，差异有显著性(P<0.05)。A组与B组在瞳孔为6mm时RMS3，RMS4，RMS6，RMSh，C12值比较，A组/B组分别为：0.165±0.064/0.098±0.045，0.127±0.034/0.059±0.025，0.040±0.014/0.028±0.010，0.218±0.059/0.129±0.040，0.137±0.057/0.048±0.037，差异有显著性(P<0.05)。其余不同直径瞳孔下的高阶像差各值比较，前者均高于后者，差异均有显著性(P<0.05)。

结论：在正常及中度散大瞳孔下，中度近视眼中曲率性近视的彗差、球差、次级球差及总高阶像差均较轴性近视眼为大。

Abstract:

AIM: To investigate the difference of ocular higher order aberrations between curvature myopia and axial myopia in moderate myopic eyes, according to the analysis of higher order aberrations in different types of moderate myopia.

METHODS: It was a prospective study. Totally 39 moderate myopic subjects(56 eyes, myopia with no astigmatism)participated in this study and were divided into two groups: group A was moderate curvature myopia group(11 patients,16 eyes),with average age 22±2 years, mean axial length of 23.89±0.13mm, mean corneal curvature 45.56±0.95D and mean diopter -4.58±0.82D. Group B was moderate axial myopia group(53 patients, 79 eyes), with average age 22±3 years, mean axial length of 25.82±0.44mm, mean corneal curvature 41.93±0.85D and mean diopter -4.50±0.78D. The values of higher order aberrations were analyzed at different pupil diameters between the two groups.

RESULTS: The comparison on mean age between the two groups had nosignificant difference as well as that on mean diopter(P>0.05). The comparisons on both average curvature of cornea and mean axial length showed significant differences(P<0.05), respectively. The values of RMS3, RMS4, RMS6, RMSh and C12 of the two groups(Group A/Group B)were 0.165±0.064/0.098±0.045, 0.127±0.034/0.059±0.025, 0.040±0.014/0.028±0.010, 0.218±0.059/0.129±0.040 and 0.137±0.057/0.048±0.037, respectively, when pupil diameter was 6mm and the comparison of the two groups had significant differences(P<0.05). Meanwhile the comparisons of ocular higher order aberrations on group A and group B also presented significant differences(P<0.05), with the former higher than the latter.

CONCLUSION: Curvature myopia had more coma, spherical aberration, secondary spherical aberration and total higher order aberrations than axial myopia in moderate myopic eyes in normal and moderately dilated pupils.