[关键词]
[摘要]
磁共振成像技术在评估视觉系统的解剖结构及功能变化方面日益得到广泛的应用,目前研究较多的磁共振技术主要包括:传统磁共振成像、弥散张量成像、功能磁共振、磁共振波谱法、锰增强磁共振等。在这些磁共振成像技术中,传统磁共振主要提供视觉系统形态学的改变,弥散张量成像及锰增强磁共振主要用于观测更微观的视觉系统结构的改变,功能磁共振可以反映视觉系统病变所引起的视觉皮层功能反应的改变,磁共振波谱法对深入研究眼部疾病的脑内代谢改变有很重要的意义。这些技术的单独或联合应用对于视觉系统相关疾病的诊断、随访监测以及疗效评估方面有着重要的价值,在临床应用方面将发挥越来越大的作用。
[Key word]
[Abstract]
Magnetic resonance imaging(MRI)is applied progressively in evaluating the anatomic structure and function of visual system, such as conventional MRI, diffusion tensor imaging(DTI), functional MRI(fMRI), magnetic resonance spectroscopy(MRS), manganese-enhanced MRI(MEMRI), and so on. Conventional MRI detects morphological changes of visual system; DTI and MEMRI are mainly applied to observe the microscopic structure changes of visual system; fMRI can examine the changes of functional response at visual cortex resulting from visual system diseases; MRS is significantly important in investigating intracerebral metabolism changes related with visual system diseases. Separate or combined application of these imaging technologies is of great value in the diagnosis, follow-up monitoring and curative effect assessment of visual system diseases, the clinical applying of these technologies will be widely spread in the future.
[中图分类号]
[基金项目]
国家自然基金青年科学基金项目资助(No.81100661); 辽宁省科技厅科技计划项目资助(No.2011225014)