方法：小儿眼外伤急诊的患儿60例，随机分为A、B两组，每组30例。A组采用小剂量氯胺酮、丙泊酚复合全麻，B组采用单纯氯胺酮全麻。分别于麻醉前、麻醉中及麻醉后观察记录生命体征、麻醉效果、副反应、眼内压、手术时间、苏醒时间、氯胺酮的用量等情况。

结果：两组患儿在麻醉后的血流动力学及呼吸功能稳定，无统计学意义(P>0.05)。A组术中副反应、眼内压增高较B组发生率明显下降，两组差异有统计学意义(P<0.05)。B组的氯胺酮用量显著高于A组，苏醒时间较A组时间明显延长，差异有统计学意义(P<0.05)。

结论：小剂量氯胺酮、丙泊酚复合全麻应用于小儿眼外伤手术，血流动力学稳定、术中眼内压保持稳定、苏醒迅速，是小儿眼外伤静脉全麻较为理想的组合。

METHODS: Sixty children with traumatic ocular disease were randomly divided into low-dose ketamine- propofol group(group A, n=30)and ketamine group(group B, n=30). The change of vital signs, effect and adverse reaction to anesthesia, intraocular pressure, the time of operation, duration of reviving and leaving operation room, ketamine mean consumption were all recorded in the preoperation, intraoperation and postoperation period.

RESULTS: There was no significant difference in thehemodynamic and respiratory function among 2 groups(P>0.05). The incidence of adverse reaction and hyper intraocular pressure was less than that of group B(P<0.05). Ketamine consumption in group B was significantly more than that in group A, recovery time were also longer in group B than those in group A(P<0.05).

CONCLUSION: The low-doseketamine combined with proprofol is a safe, efficacy anesthesia with stable hemodynamic function and intraocular pressure, quicker recovery and less adverse effect in pediatric ocular trauma surgery.