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[摘要]
目的:探讨以眼后节表现为主的梅毒性眼病的临床特点。
方法:回顾性病例研究。回顾性分析2007-01/2012-01本院收治的首诊于眼科的梅毒性眼病13例23眼,分析其临床表现、治疗方法、预后等。13例患者按神经梅毒除1例因青霉素过敏予静滴头孢曲松治疗,其余全部予静滴青霉素治疗。
结果:患者13例中,9例17眼患者表现为脉络膜视网膜炎,2例3眼患者表现为视神经视网膜炎,1例1眼患者表现为视神经炎,1例2眼患者表现为渗出性视网膜脱离。抗梅毒治疗后,所有炎症消退,12例22眼患者视力提高,平均视力0.56±0.23。患者RPR滴度下降4倍,平均1:16.6。
结论:梅毒性眼病表现多样,容易漏诊、误诊,临床上应提高警惕,及早发现,及早治疗。
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[Abstract]
AIM:To investigate the clinical features of ocular syphilis.
METHODS:The clinical data of 13 patients with active ocular syphilis were retrospectively reviewed. The diagnosis was made first in eye clinic. Twelve patients received systemic penicillin therapy and 1 patient was treated with ceftriaxone due to penicillin allergy.
RESULTS:The major ocular manifestations included chorioretinitis(9 cases, 17 eyes), neuroretinitis(2 cases, 3 eyes), optic neuritis(1 case, 1 eye), exudative retinal detachment(1 case, 2 eyes). The mean follow-up visual acuity was 0.56±0.23, and follow-up of(rapid plasma reagin)RPR titer was 1:16.6.
CONCLUSION:Ocular syphilis has different manifestations, which is easy to misdiagnosis and missed diagnosis. Oculist should be vigilant to detect and treat early.
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