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[摘要]
目的:探讨超声及Schempflug原理测量中央角膜厚度(CCT)的差异及其临床意义。
方法:对2011-07我院门诊角膜正常的患者86例150眼分别用非接触式眼压/角膜厚度测量仪NT-530P和Pentacam眼前段分析仪、超声角膜测厚仪三种仪器测量CCT。用SPSS 17.0统计学软件对不同方法测量的结果进行单因素方差分析和Pearson相关性分析,并绘制Bland-Altman散点图,分析不同测量方法之间的一致性。
结果:三种仪器所测得CCT测量结果分别为:NT-530P 541.19±32.47μm,Pentacam 542.76±32.40μm,超声角膜测厚仪539.88±31.98μm。三种检查仪测量结果差异无统计学意义(F=0.290,P=0.748),且两两之间高度相关(r1=0.954, r2=0.973, r3=0.948)。以A超角膜测厚仪测量的CCT为基准把患者分为3组:CCT≤520μm,520μm570μm,对三种仪器测量的结果进一步对比分析,三组中的各仪器测量结果均无统计学差异(P>0.05)。结论:三种方法测量的CCT差异无统计学意义(P>0.05),且具有很好的相关性。
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[Abstract]
AIM: To investigate the differences in central corneal thickness(CCT)measurements using pachymetries of ultrasound and Schempflug system.
METHODS: The CCT of 150 healthy corneal eyes(from 86 cases)were measured with non-contact tonometry/pachymetry NT-530P, Pentacam and ultrasonic pachymetry. The consistency of the measurements was statistically analyzed by one-way ANOVA and Bland-Altman plot. The differences were analyzed by Pearson correlation coefficients.
RESULTS: The CCT values measured with non-contact tonometry/pachymetry NT-530P, Pentacam and ultrasonic pachymetry were(541.19±32.47)μm,(542.76±32.40)μm and(539.88±31.98)μm, respectively. No statistically significance differences were found among the three instruments(F=0.290, P=0.748), and there were high correlations among them(r1=0.954, r2=0.973, r3=0.948). The sample(150 eyes)was divided into 3 groups according to the CCT measurements obtained with ultrasonic pachymetry for further analysis: CCT≤520μm,520μm 570μm. The 3 groups have high relation and good consistency(P>0.05). CONCLUSION: There are no statistically significant differences among the three instruments, and the correlations of them are high.
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