目的：探讨LASIK术前屈光不正患者眼压（intraocular pressure,IOP）、中央角膜厚度（central corneal thickness,CCT）、屈光度和角膜曲率之间的关系。方法：屈光不正患者220例440眼,用非接触式眼压计测量患者的眼压、超声角膜测厚仪测量患者中央角膜厚度、电脑验光仪测量等效球镜度数和曲率,两两比较各测量项目之间的相互关系,并进行统计学处理。结果：各组屈光不正患者眼压与中央角膜厚度之间呈正相关关系（r=0.568, 0.534, 0.413, 0.412；P＜0.001）。屈光不正患者屈光度与中央角膜厚度、曲率、眼压之间相关性无统计学意义（r=-0.078,0.068,-0.077;P=0.052, 0.073,0.058）。屈光不正患者曲率与眼压、中央角膜厚度之间比较差异无统计学意义（r=0.004,-0.058;P=0.917,0.157）。结论：屈光不正患者眼压与中央角膜厚度之间呈正相关,随着角膜厚度的增加眼压升高。

AIM:To explore the relationship of intraocular pressure (IOP), central corneal thickness(CCT),refraction dioptres and corneal curvature before LASIK.METHODS: Totally 220 cases (440 eyes) with refractive errors were enrolled and the data were measured by non-contact tonometer, ultrasound pachymetry and computer refractor. Various measurements were compared and analyzed statistically.RESULTS: There was a positive correlation between IOP and CCT in patients with refractive errors（ r=0.568,0.534, 0.413, 0.412；P<0.001）. There was no statistically significant correlation between refraction dioptres and CCT, IOP, corneal curvature in refractive errors（r=-0.078,0.068,-0.077; P=0.052, 0.073, 0.058）. There was no statistically significant correlation between corneal curvature, IOP and CCT in refractive error（r=0.004,-0.058; P=0.917, 0.157）.CONCLUSION: There is a positive correlation between IOP and CCT in patients with refractive errors.