目的：观察复方樟柳碱注射后短期内瞳孔和眼压的变化。 方法：对纳入治疗的74 例148眼，在复方樟柳碱注射前即刻和注射后15，30，60和120min分别用标准的瞳孔专用尺和非接触眼压计测量瞳孔横径和眼压；各项量化数据采用SPSS 18.0统计分析软件处理，组内前后对比采用配对t检验。 结果：复方樟柳碱注射后至少在短时间（120min）内总体眼压呈下降趋势，统计学分析显示眼压下降差异有显著性（P＜0.01）。复方樟柳碱注射后15min瞳孔较用药前扩大（P＜0.01），并持续到60min后开始回收。 结论：复方樟柳碱注射液颞浅动脉区皮下注射后短时间内对眼压波动影响小，且大多数患者的眼压呈下降趋势；该药引起的散瞳作用轻微且短效，不足以诱发高眼压。

AIM:To observe the short-term changes of pupil and intraocular pressure（IOP） after compound anisodine injection. METHODS:In 74 cases (148 eyes), the pupil diameter and IOP were measured by classical pupil diameter ruler and non-contact tonometer immediately before and 15, 30, 60, 120 minutes after compound anisodine injection. Statistical analysis was performed using the SPSS 18.0 program and paired t-test was used in our study. RESULTS：IOP was decreased after compound anisodine injection at least in a short time(within 120 minutes),and the decrease is statistically significant(P＜0.01).The pupil was bigger at 15^th minute after compound anisodine injection than before the therapy(P＜0.01),which is last until 60^th minute. Then the pupil became smaller. CONCLUSION:Compound anisodine superficial temporal subcutaneous injection has little effect on IOP fluctuation and IOP of most patients was decreased. Mydriasis effect of the drug is minor and short-acting, which can not induce ocular hypertension. "