脉络膜黑色素瘤的治疗进展

Treatment progress of choroidal uveal mela- noma

摘要:

脉络膜黑色素瘤（choroidal melanoma，CM）是成年人眼球最常见的眼内恶性肿瘤。CM恶性程度高、发生转移早、预后差，早期诊断及选择合理治疗方式对改善患者的预后至关重要。近年来，眼球摘除术作为治疗CM的传统方法已受到挑战。针对不同部位和大小的肿瘤及患者具体情况采取不同的疗法或联合治疗已成为CM的治疗原则。本文就CM的治疗进展进行综述，为降低转移率和死亡率提供相关依据。

Abstract:

Choroidal melanoma(CM) is the most common intraocular tumor in adults. It is a major ocular problem that could threaten the patients life and requires early diagnosis and treatment. During the past decade, there has been a trend in the management of CM from enucleation to conservative nonenucleation treatments such as thermotherapy, plaque radiotherapy, charged-particle radiotherapy, and local resection. Recent researches have shown that combined modality therapy has been more and more popular now. We reviewed the current literature for trials and case reports on choroidal melanoma and discusses its diagnosis and current treatment.