目的：探讨采用掀瓣行二次准分子激光原位角膜磨镶术(LASIK)治疗LASIK术后欠矫和回退的有效性及安全性。 方法：对LASIK术后因欠矫和屈光回退的近视眼患者25例36眼采用掀开原角膜瓣的方法，对瓣下基质床行再次准分子激光消融。术后随访1a，观察视力、屈光度及手术并发症。 结果：再次术后1，3，6，12mo，平均裸眼视力（UCVA）从术前的0.39±0.16分别提高为0.92±0.17，1.01±0.16，1.03±0.16，1.04±0.18，术前UCVA与术后各时间点比较均具有极显著差异(P<0.01)；术前平均等效球镜度数为-1.87±0.64D，术后12mo的等效球镜度数平均为0.21±0.43D，两者比较有极显著性差异(P<0.01)。 结论：采用掀瓣的LASIK提升术治疗LASIK术后欠矫和屈光回退，此方法是安全、有效的。

AIM：To discuss the efficacy and safety of lifting flaps for laser in situ keratomileusis (LASIK) enhancement. METHODS：Totally 25 cases (36 eyes) of post-LASIK with residual refractive error were performed enhancement using lifting flaps, then ablated corneal stroma by excimer laser procedure. Postoperative follow-up survey included visual acuity, refractive error and complications for 1 year. RESULTS：The average uncorrected visual acuity improved from preoperative 0.39±0.16 to postoperative 092±0.17, 1.01±0.16, 1.03±0.16, 1.04±0.18 at 1 month, 3, 6, 12 months. The pre-operative mean spherical equivalent changed from -1.87±0.64D to 0.21±0.43D at post-enhancement 12 months. There was significant difference between them (P<0.01). CONCLUSION： Ｌifting flaps for LASIK enhancement is safe and effective to treat LASIK postoperative undercorrection and reftactive regression treatment.