目的:了解盐酸环喷托酯滴眼液和复方托品卡胺滴眼液在散瞳验光中麻痹睫状肌的临床效果,客观地对其评价以指导临床工作。 方法:随机抽取2010-12/2011-03期间的60例120眼屈光不正（近视和远视各占50%）患者，年龄12～40岁,利用国产复方托品卡胺滴眼液滴眼散瞳先后对其进行散瞳4次, 45min以后,对其进行检影验光,并利用综合验光仪测定其残余调节量,第2d用盐酸环喷托酯眼液进行复验。 结果:远视组盐酸环喷托酯滴眼液和复方托品卡胺两者验光结果差异较大（P＜0.01）；近视组两者验光差异较小（P＜0.05），但是仍然具有统计学差异。 结论:临床上对于屈光不正患者的屈光检查,复方托品卡胺滴眼液是一种有效的睫状肌麻痹剂,但因注意到其麻痹睫状肌及放松调节的有限性,特别在远视患者应灵活结合其他放松调节如盐酸环喷托酯眼液的方法获取最终的配镜处方。

AIM:To investigate the effect of Cyclogyl and compound tropicamide on cycloplegia with objective assessment to guide their clinical work. METHODS: Totally 60 cases(120 eyes) of myopia and hyperopia(each of 50%) aged 12 to 40 years from 2010/12 to 2011/03 were randomly selected.They were conducted mydriasis with domestic compound tropicamide eye drops 4 times, and retinoscopy 45 minutes later, and measured the amount of residual accommodation with integrated refractor.They were reinspected with Cyclogyl on the second day. RESULTS: In the hyperopia group, there were significant differences in refraction results between Cyclogyl and compound tropicamide (P<0.01); there were less differences in the myopia group (P<0.05), but still statistically significant. CONCLUSION:Clinically for refraction of patients with refractive error, compound tropicamide eye drops is an effective cycloplegic, but because of its limited cycloplegia and relaxation of accommodation, especially in hyperopic patients, it should be integrated with other relaxation methods, such as Cyclogyl, to get the final glasses prescription.