目的：探讨老年性耳聋是否为早期诊断假性剥脱综合征(pseudoexfoliation syndrome,PES)的临床预测参数。 方法：这是一项前瞻性病例对照研究。单眼或双眼PES患者组成研究组，另有30例老年性耳聋患者。测量0.5，1，2和4kHz纯音听阈水平。同时记录鼓室测压高峰值和瞬态诱发耳声发射测试结果。所有受试者进行了详细的眼科检查。 结果：PES组与老年性耳聋的听力水平分布不同。轻度听力丧失（21~40分贝）第2组高于第1组。对PES和老年性耳聋患者各检查频率之平均听力阈值进行直接比较。比较PES和老年性耳聋患者的平均纯音听阈可发现两耳之间存在显著性差异。然而高频率（4kHz）时， 两耳之间无统计学意义。 结论：所有在耳鼻喉科诊断为老年性耳聋的患者不应该进行眼科检查。在临床实践中，此种检查是时间和金钱的巨大浪费。

AIM: To find out if presbyacusis is a predictive clinical parameter for early diagnosis of pseudoexfoliation syndrome (PES). METHODS: This is a prospective, case-control study. 30 patients with PES in one or both eyes constituted the study group and the other 30 presbyacusis patients were in control group. Pure-tone hearing threshold levels (HTLs) were measured at 0.5, 1, 2, and 4 kHz. Tympanometric peak values and transient evoked otoacoustic emissions (TEOAE) testing results were also recorded. All subjects underwent a detailed ophthalmic examination. RESULTS：Distribution of the hearing levels was different between the study group and control group. Mild hearing loss (21-40 dB) was higher in control group than that in study group. Mean hearing thresholds at each of the examined frequencies were compared directly between the two groups. Clinically significant differences were found when we compared mean pure-tone HTLs between the 2 ears of the two groups. However, there was not a statistically and clinically significant difference between the 2 ears mean pure-tone HTLs at high frequency (4 kHz). CONCLUSION：We concluded that patients who are diagnosed with presbyacusis in ear, nose, and throat should not be performed any ophthalmic examinations, which would save time and money in daily clinical practice.