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目的:分析眼睑基底细胞癌的临床及组织病理学特征,提高诊断水平。 方法:回顾性病例分析。收集我院2001-08/2011-08门诊及住院眼部基底细胞癌患者91例91眼,分析患者的临床和病理资料,所有病例采用常规石蜡切片、HE染色,部分病例常规HE切片诊断困难加做免疫组织化学染色。 结果:本组患者眼睑基底细胞癌多发生于下睑和内眦,肿瘤为结节状,瘤细胞呈基底细胞样,HE染色和免疫组织化学有助于诊断。 结论:眼睑基底细胞癌患者首诊多数得不到正确诊断和及时有效的治疗,导致病情日益加重。眼睑基底细胞癌主要应与睑板腺癌、恶性黑色素瘤、鳞状细胞癌等进行鉴别。
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[Abstract]
AIM:To analyze clinical and histopathological features of eyelid basal cell carcinoma and improve the diagnostic level. METHODS:Retrospective analysis of case series. Ninty-one cases (91 eyes) of basal cell carcinoma of eyelid of outpatients and inpatients dating from August 2001 to August 2011 were collected to review clinical and histopathological features. Parafin section and HE stain were applied to all cases. Immunohistochemical staining was further applied to some cases with diagnostic difficulties. RESULTS:Basal cell carcinoma of these cases occurred mostly in lower eyelid and inner canthus. The carcinoma was nodular and carcinoma cells appeared like basal cells. HE stain and immunohistochemistry were helpful fo diagnosis. CONCLUSION:Accurate diagnosis and timely treatment were not given to patients suffering from basal cell carcinoma of eyelid in the first diagnosis, which worsened their conditions. Basal cell carcinoma of eyelid should be differentiated from meibomian gland carcinoma, malignant melanoma, epidermoid carcinoma, etc
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