目的：探讨规模化白内障手术中高龄及其伴全身疾病患者安全性。 方法：回顾性分析“爱心光明行”活动中高龄及其伴全身疾病患者的临床资料。 结果：本组高龄伴全身疾病患者213例（90.6%），其中循环系统疾病、代谢性疾病、呼吸系统疾病分别占65.1%，13.6%和11.1%。术前因首次全身疾病评估暂缓手术25例（10.6%），经有效治疗后手术。手术脱残率95.4%，脱盲率84.2%，12例视力＜0.1患者眼底检查均有不同程度的眼底病变。 结论：加强术前综合因素评估，充分治疗全身疾病，严格掌握手术适应证，术中监护，操作轻巧，手术时间10～15min，是保证规模化白内障手术中高龄或伴全身疾病患者安全性的有效措施。

AIM:To discuss the security on patients with eld or concomitant systemic disease in scale cataract surgery. METHODS:The clinical data of 235 patients above 75 years or with systemic disease in “love and light” activity were retrospectively analysed. RESULTS:There were 213 cases (257 eyes) with systemic disease(90.6%). The ratios of circulation system disease, metabolic disease, and respiratory system disease were 65.1%, 13.6% and 11.1%, respectively. There were 25 cases (10.6%) deferring surgery because of the first preoperative evaluation of systemic disease and the surgery was done after effective treatment. The surgery off-disability and off-blindness rates were 95.4% and 84.2%, respectively. 12 cases with vision <0.1 had different degree of fundus disease. CONCLUSION:Strengthening preoperative comprehensive assessment, treating systemic disease fully, mastering operation indication strictly, monitoring in operation, operating legerity and 10-15 minutes surgery time were the effective measures to guarantee the security of patient with eld or concomitant systemic disease in scale cataract surgery.