探讨玻璃体腔注射曲安奈德联合激光治疗糖尿病性黄斑水肿(DME)的疗效。 方法：对44例65眼DME患者首先采用玻璃体腔注射曲安奈德进行治疗，术后1mo采用美国Coherent公司的Novus Omni多波长氪离子激光仪，对局限性黄斑水肿进行局部直接光凝，对弥漫性水肿及囊样水肿进行格栅样光凝。 结果：所有患者中显效27眼，有效33眼，无效5眼，显效率41.5%，总有效率92.3%。随访期间无视网膜脱离、眼内出血、感染性眼内炎及其它并发症发生。 结论：玻璃体腔注射曲安奈德联合激光光凝具有疗效显著、不良反应少、能够有效提高患者视力、减轻黄斑水肿等特点，是DME的有效治疗方法。

To evaluate the effects of intravitreal triamcinolone acetonide (TA) injection combined with laser photocoagulation on diabetic macular edema（DME）. METHODS: Fourty-four cases (65 eyes) with DME were selected and treated by intravitreal TA injection first and laser photocoagulation at postoperative 1 month. RESULTS:In this group, 27 eyes were markedly effective,33 eyes were effective.Significant efficiency was 41.5%,total efficiency was 92.3%.Retinal detachment, intraocular hemorrhage, infectious endophthalmitis and other complications could not be found during follow-up. CONCLUSION:Intravitreal TA injection combined with laser photocoagulation has significant curative effect, less adverse reaction and can significantly improve visual acuity, relieve macular edema. It is a safe and effective approach to patients with DME.