目的：观察并分析外路小梁切开联合小梁切除术治疗原发性先天性青光眼的临床疗效。 方法：收集原发性先天性青光眼患者51例89眼，应用外路小梁切开联合小梁切除术进行治疗，观察术后眼压、角膜横径、杯/盘比值、滤过泡情况及手术并发症并分析其临床疗效。 结果：术后平均随访（15.21±6.50）mo，术后1,6,12mo手术成功率分别为97%，90%，90%。术后平均眼压较术前显著降低(P<0.01)；杯/盘比值较术前明显减小（P<001）；角膜横径手术前后差异无显著意义（P=0.495）；手术失败者角膜横径较术前增大（P<0.05）。手术并发症主要有不同程度的前房出血和术后浅前房等。 结论：外路小梁切开联合小梁切除术是治疗原发性先天性青光眼安全有效的手术方式之一

To study the clinical effects of 1.8mm coaxial microincision phacoemulsification and negative power intraocular lens implantation for the patients with cataract and extreme myopia. METHODS: A retrospective study was carried out on 98 eyes of 71 cases with a history of cataract and extreme myopia. The patients received phacoemulsification and a negative power intraocular lens implantation. Preoperative axial length, visual acuity, best-corrected visual acuity(BCVA) were recorded. Intraoperative and postoperative complications were observed. The follow-up time was from 3 to 6 months. Postoperative visual acuity, BCVA were recorded. RESULTS: The mean preoperative axial length was 29.33±1.95mm. The preoperative visual acuity of the patients were all bellow 0.05. The postoperative uncorrected visual acuity (UCVA )achieved 0.3 in 60 eyes (61%) and the BCVA achieved 0.5 in 48 eyes (49％) after the operation. Only 1 eye had posterior capsule rupture during the operation. 20 eyes had binocular disturbances. 6 eyes developed posterior capsule opacification and 5 eyes were performed neodymium: YAG laser posterior capsulotomy. There were no retinal detachment or choroidal detachment during the follow-up. CONCLUSION: The 1.8mm coaxial microincision phacoemulsification and negative power intraocular lens implantation is safe and effective for cataract and extreme myopia.