目的：探讨高海拔地区哈萨克族翼状胬肉患者不同方法治疗的效果。 方法：将66例69眼患者随机分为两组，分别采用翼状胬肉显微切除加自体角膜缘干细胞移植联合丝裂霉素C术（33例34眼）和翼状胬肉显微切除+丝裂霉素C术（33例35眼），术后随诊1~2d。 结果：角膜上皮愈合时间：角膜缘干细胞组为3~5（平均4.5±2.4）d，胬肉切除组5~8（平均6.5±2.6）d，两组比较差异有统计学意义（t=3.317，P<0.05）。角膜缘干细胞组有1眼复发，复发率3%，胬肉切除组8眼复发，复发率为22%，两组比较差异有统计学意义（χ²=4.389,P<0.05）。 结论：在高海拔地区，由于气压低、风沙大、干燥、紫外线辐射强等特点，造成少数民族患病率增高。采用胬肉切除加自体角膜缘干细胞移植联合丝裂霉素C治疗，角膜创面修复快，复发率低，是一种安全、有效、值得推广应用的方法。

AIM:To investigate the effect on high altitude Kazak patients with pterygium treated with different methods. METHODS:Sixty-six cases ( 69 eyes) were randomly divided into two groups, using microsurgical excision of pterygium with limbal stem cell transplantation combined with mitomycin C operation ( 33 cases, 34 eyes) and pterygium microscopic resection combined with mitomycin C operation ( 33 cases,35 eyes) respectively,postoperative follow-up lasted 1-2 years. RESULTS:The corneal epithelial healing time was 3-5(4.5±2.4)days in corneal limbal stem cells group, 5-8(6.5±2.6)days in pterygium excision group, there was significant difference between two groups(t=3.317,P<0.05).Corneal limbal stem cell group had 1 eye recurred, the relapse rate was 3%, 8 eyes recurred in pterygium excision group, the recurrence rate was 22%, there was significant difference between two groups (χ² = 4.389,P<0.05). CONCLUSION:At high altitude, due to low air pressure, large wind and sand, drying, and strong ultarvidet radiation,the prevalence rate of minority nationalities increases.Pterygium excision with autologous limbal stem cell transplantation combined with mitomycin C treatment in patients has fast corneal wound healing and low recurrence rate, which is a safe, effective method and worthy of promotion and application.