目的:观察有晶状体眼后房型可接触式人工晶状体植入矫治中高度近视的临床效果。 方法:选择15例24眼中高度近视(-3.50~-15.50D)患者行有晶状体眼后房型可接触式人工晶状体植入术，对其术前和术后1，3，6和12mo的常规检查结果分析，评价手术的安全性、有效性、可预测性、稳定性和并发症。 结果:术前平均最佳矫正视力0.84±0.24(0.4~1.2)，术后平均裸眼视力0.90±0.29(0.5~1.5),差异无显著统计学意义（P>0.05）。平均球镜度数：术前-3.50~-15.50（平均-10.19±3.37）DS,术后1.00~-1.25（平均-0.20±0.68）DS,差异有显著统计学意义（P<0.05）。平均散光度数：术前-1.98±1.62DC,术后-0.41±0.58DC，差异有显著统计学意义（P<0.05）；术前前房深度3.08±021mm,术后2.25±0.32mm，差异有显著统计学意义（P<0.05）；手术前后眼压比较差异无显著性意义;手术无严重并发症发生。 结论:后房型人工晶状体可接触式人工晶状体植入矫治中高度近视具有安全、有效、可预测性、可逆性;远期效果有待于进一步随访观察。

AIM:To assess the clinical outcomes of implantation of a lens consisting of a biocompatible collagen copolymer (Visian implantable Collamer lens \[ICL\]; STAAR Surgical, Nidau, Switzerland) for moderate to high myopia. METHODS:Totally 24 eyes of 15 patients with myopic refractive errors of -3.50 to -15.50 diopters (D) who underwent ICL implantation and routine postoperative examinations were evaluated. Before and 1day,1 month, 3, 6 and 12 months after surgery, the safety, efficacy, predictability, stability, and adverse events of the surgery were assessed. RESULTS:The uncorrected visual acuity was 0.90±0.29(0.5-1.5) after surgery, higher than the mean preoperative best-corrected visual acuity 0.84±0.24(0.4-1.2) with non-significance (P>0.05). The average values for spherical refractions were -0.20±0.68（1.00- -1.25）DS after surgery, lower than that of preoperative -10.19±3.37(-3.50--15.50)DS with remarkable significance (P<0.05). The average values for cylindrical refractions were -0.41±0.58DC after surgery, lower than that of preoperative -1.98±1.62DC with remarkable significance (P<0.05). The average anterior chamber depth were 225±0.32mm after surgery, lower than that of preoperative 3.08±0.21mm with remarkable significance (P<0.05).There was not significant difference between preoperative and postoperative intraocular pressure. The surgery was without serious complications. CONCLUSION: Implantation of ICL is safe and effective and provides predictable and stable refractive results in the treatment of moderate to high myopia during one-year observation, suggesting its viability as a surgical option for the treatment of such eyes.