目的：通过OCT方法检查弱视患者的注视性质，思考和审视偏心注视的机制，指导弱视治疗。 方法：对一组3~12岁儿童远视屈光性重度弱视患儿31例40眼治疗前后做黄斑光学相干断层扫描(OCT)检查，观察其注视性质的变化。 结果：在31例40眼中，中心注视眼占63%，偏心注视眼占38%。单眼患者中心注视与偏心注视各占50%，双眼患者78%为中心注视，22%为偏心注视。治疗后15只偏心注视眼，分别在0.2~0.5视力之间全部转成中心注视，时间为1mo~2a。合并外斜和调节性内斜没有影响偏心注视转中心注视, 且无论中心注视及偏心注视，其视力恢复对比观察，无明显差异。 结论：采用OC T检查弱视眼注视性质客观、简便。在治疗过程中随着视力的提高，偏心注视转化为中心注视说明中心凹锥细胞功能被唤醒并且功能逐渐增强。

"AIM: To observe fixation behaviors in amblyopes by optical coherence tomography（OCT）and to explore the possible mechanism of eccentric fixation so as to guide amblyopia treatment. METHODS: OCT was performed on a group of 31 cases (40 eyes) aged 3 to 12 with severe amblyopia of hyperopia refractive error respectively before and after treatment. The results were recorded and compared to detect the change and mode of their visual fixation. RESULTS: Among the 31 cases (40 eyes), 63% was foveal fixation, and 38% was eccentric fixation. For uniocular patients, eccentric and foveal fixation shared the same percentage of 50%. For binocular patients, eccentric fixation was present in 22% of the total cases; the remaining 78% was foveal fixation. After treatment, all of the 15 eyes with eccentric fixation visual acuity between 0.2-0.5 were successfully converted to foveal fixation. The time of treatment varied from one month to two years. Combined exotropia and accommodation esotropia did not affect the conversion. Moreover, regardless of the mode of fixation, there was no significant difference in the final visual acuity achieved after treatment. CONCLUSION: OCT examination is an objective and easy-to-operate means to assess of fixation behaviors in amblyopes. With the improvement of visual acuity during treatment, the patient-s eccentric fixation converted to foveal fixation. "