目的:检测2型糖尿病合并老年性白内障患者血清及眼房水中铬元素的含量,并探讨其临床意义。方法:采用石墨炉原子吸收法测定患者血清及房水中铬的含量,试验组:糖尿病(2型)合并白内障患者19例,对照组:健康的老年性白内障患者21例。结果:试验组的血清及房水铬元素含量分别为(3.79±1.17)μg/L,(0.97±0.35)μg/L,明显低于对照组(4.50±0.92)μg/L,(1.43±0.68)μg/L,且两组比较差异均有统计学意义(t=-2.139,P<0.05;t=-2.653,P<0.05),两组血清及房水中铬元素含量无显著相关性(r=-0.142,P>0.05)。结论:铬元素在糖尿病合并老年性白内障患者的发生及发展过程中具有重要作用。

AIM:To evaluate the aqueous humor and serum levels of chromium(Cr) in cataract patients with and without 2 type diabetes mellitus·METHODS:Levels of Cr were measured using atomic absorption spectrometry in the serum from 40 patients and aqueous humor aspirates taken during anterior segment surgery from 19 eyes of 19 patients who had diabetic cataracts(diabetic group)and from 21 eyes of 21 patients who had senile cataract only(control group)·RESULTS:The mean aqueous humor Cr concentration in eyes with diabetes cataract was significantly lower than that from eyes with senile cataract(P<0.05).There was also a statistically significant difference between the serum Cr concentrations of the diabetic group and the control group(P<0.05).Serum and aqueous humor chromium content in both groups showed no significant correlation(r=-0.142,P>0.05)·CONCLUSION:The aqueous humor and serum Cr levels are decreased in eyes with diabetic cataract.Cr has an important role in the development process of cataract in patients with diabetes.