目的:探讨翼状胬肉术前使用雄矾散,术中使用生物羊膜移植对减轻角膜损伤减少翼状胬肉复发的临床效果。方法:选取翼状胬肉43例56眼,其中原发性胬肉45眼,复发性11眼,均采用术前使用雄矾散,术中生物羊膜移植术治疗,随访12～18mo,观察手术效果。结果:翼状胬肉治愈52眼(93%)。复发4眼(7%),其中2眼为原发性翼状胬肉,2眼为复发性翼状胬肉。雄矾散未引起角膜化学损伤,且角膜创面光滑平整。羊膜移植未发现角巩膜溶解坏死、溃疡、感染等并发症。结论:雄矾散联合生物羊膜移植治疗翼状胬肉效果良好,角膜创面光滑平整,且修复快,复发率低,无排斥反应,是一种理想的手术方法,特别是医疗条件有限的基层医院更应推广使用。

AIM:To investigate the clinical effects on reducing the corneal ingury and recurrence of pterygium by combined using of preoperative Xiongfansan and intraoperative biological amniotic membrane transplantation.METHODS:Totally 43 patients(56 eyes) with pterygium,including primary 45 eyes and recurrent 11 eyes,were treated with preoperative Xiongfansan and intraoperative biological amniotic membrane transplantation,and followed up 12-18 months.RESULTS:Totally 52 eyes(93%) were cured,and recurrence was in 4 eyes(7%) with primary 2 eyes and recurrent 2 eyes of pterygium.Xiongfansan did not cause severe chemical damage on cornea,the complications including melting necrosis,ulceration and infection did not occur on corneosclera.CONCLUSION:The effects of combined using of Xiongfansan and biological amniotic membrane transplantation on pterygium is well,with quick repair,low recurrence rate and no rejection.It is an ideal method and should be widely used.

R779.6