目的:观察玻璃体切割术中保留晶状体对角膜内皮细胞的保护作用。方法:选择视网膜脱离合并增生性玻璃体视网膜病变接受了玻璃体切割术的32例32眼患者,其中14例因合并白内障或前段增生性玻璃体视网膜病变术中切割了晶状体,另外18例保留了晶状体。用角膜内皮显微镜测定术前和术后2wk内角膜内皮细胞,观察细胞的形态变化,并对细胞的4项定量指标进行统计学分析。结果:细胞形态学改变以术后无晶状体眼更明显。从细胞参数改变上看,术后4项定量指标有改变,与术前相比,有晶状体眼组差异无显著性(P>0.05);无晶状体眼组差异有显著性(P<0.05)。结论:玻璃体切割术时,晶状体的屏障功能减少了多因素对角膜内皮细胞的损害,保留晶状体可对角膜内皮细胞产生一定的保护作用。

AIM:To observe the preventive effect of lens on corneal endothelium during vitreoretinal surgeries.METHODS:Totally 32 patients(32 eyes)underwent vitrectomy,part of the lens(18 cases)were retained,part of the lens were not retained(14 cases).Pictures of corneal endothelium were taken with specular microscopy before operation and within two weeks after operation.Morphological changes of the cells were observed directly,and the cells’ four parameters were analyzed by statistics.RESULTS:The changes of abnormal morphology of cells were more obvious in the postoperative aphakia.Comparing the cells’ four parameters with preoperation,there were no statistically significant differences in the postoperative phakia(P>0.05).There were statistically significant differences in the postoperative aphakia(P<0.05).CONCLUSION:In vitrectomy,the barrier function of lens can reduce the damage of various factors on corneal endothelial cells,retained lens play a protective effect on the corneal endothelial cells.

R779.6