目的:了解原发性眼睑肿瘤的组织病理学特征及发病率。方法:收集第三军医大学附属西南眼科医院2003-01/2009-12门诊及住院治疗的291例原发性眼睑肿瘤患者的临床病理资料进行回顾性分析。结果:良性眼睑肿瘤172例(59.1%),其构成位于前10位的依次为:乳头状瘤、色素痣、炎性肉芽肿、皮样囊肿或表皮样囊肿、淀粉样变性、疣、血管瘤、黄色瘤、浆细胞肉芽肿、毛发上皮瘤。恶性眼睑肿瘤119例(40.9%),其构成位于前5位的肿瘤依次为:基底细胞癌、鳞状细胞癌(含梭形细胞癌)、皮脂腺癌、恶性淋巴瘤、恶性黑色素瘤。对眼睑三大恶性肿瘤的临床流行病学资料进行了总结分析,讨论了眼睑肿瘤切除术后的眼睑修复方法。结论:眼睑肿瘤临床病理分类繁多,对病变进行临床病理分析有助于正确的诊断及治疗。

AIM:To investigate the histopathologic features and incidence of primary blepharal neoplasms.METHODS:The clinical pathological data of 291 primary blepharal neoplasms in Southwestern Eye Hospital from January 2003 to December 2009 were collected and analyzed retrospectively.RESULTS:Benign blepharal neoplasms were 172 cases(59.1%),the top ten in the ranking in turn were papilloma,pigmented nevus,inflammatory granuloma,dermoid cyst or epidermoid cyst,amyloid degeneration,warts,hemangioma,xanthoma,plasma cell granuloma,trichoepithelioma.Malignant blepharal neoplasms were 119 cases(40.9%),the top five in the ranking in turn were basal cell carcinoma,squamous cell carcinoma(including spindle cell carcinoma),sebaceous gland carcinoma,malignant lymphoma,malignant melanoma.The clinical epidemiological data of the top three malignant blepharal neoplasms were summarized.The eyelid restoration after neoplasms ablation were discussed.CONCLUSION:The classification of blepharal neoplasms was various,the clinical pathological analysis of primary blepharal neoplasms was helpful to correct diagnosis and treatment.

R739.7