高度近视与ABO血型抗原的相关性研究

Analysis of the correlation between high myopia and ABO blood group

摘要:

目的:通过对高度近视患者进行ABO血型相关性分析,了解各血型与高度近视发病的关系,指导高度近视的治疗与预防。方法:对70例高度近视患者与72例体检者(对照组)采用试管凝集法进行ABO血型检测,分别进行男女性别及血型分布比较。结果:高度近视血型分布为O>B>A>AB,女性多于男性,A血型抗原与O血型抗原比较,差异有显著性(χ2=5.9510,P<0.05),其它各血型比较,差异均无显著性。结论:高度近视患者女性明显多于男性;A型抗原的遗传因子与防止高度近视的发生有一定的相关性;同时也揭示对于O型血女性应更加重视近视的预防与治疗,将对预防高度近视的发生可能具有较为重要的意义。

Abstract:

AIM:To investigate the relationship between high myopia incidence and ABO blood group by correlation analysis of myopia incidence of different blood groups, hoping to find a way to treat and prevent high myopia. METHODS:ABO blood group of 70 high myopia patients and 72 normal people (control group) were tested by tube agglutination, and the distributions were compared according to sex and ABO blood group. RESULTS:For high myopia , the distribution was O>B>A>AB, female group had higher incidence than male, and there was significant difference between A blood group and O blood group (χ2=5.9510,P<0.05). Comparing the other blood groups, there were no significant differences of each other. CONCLUSION:Women tended to have higher incidence than men in high myopia. The genetic factors of A blood group antigen had some relationship with prevention of high myopia. The fact also revealed that female of O blood group should pay more attention to prevention and treatment of high myopia at the same time, which had important meaning in high myopia prevention.