糖尿病视网膜病变患者的心电图改变与临床分析

Electrocardiogram changes in diabetic retinopathy patients and its clinical analysis

摘要:

目的:探讨2型糖尿病患者伴糖尿病视网膜病变(diabetic retinopathy,DR)的心电图改变规律及临床意义。方法:总结2009-06/2011-03在我院眼科住院的113例DR患者的心电图和血脂、糖化血红蛋白水平等资料,并对其进行回顾性分析。结果:DR患者心电图的异常表现以ST-T改变为多见。非增殖期心电图异常25例(61.0%),增殖期59例(81.9%),组间差异显著。在心电图异常的DR患者中处于增殖期的病例比例明显高于心电图正常组。与心电图正常组相比,心电图异常组也伴有糖化血红蛋白平均水平的升高,差异具有显著统计学意义(P<0.01)。心电图的异常组与正常组间甘油三酯和胆固醇水平差异不显著。结论:DR作为糖尿病严重眼部并发症多伴心血管系统病变的发生和血糖控制不良的情况。

Abstract:

AIM:To investigate the clinical value and law of electrocardiogram(ECG) changes in type 2 diabetes mellitus patients with diabetic retinopathy(DR). METHODS:The study was based on 113 patients with type 2 diabetes mellitus in the ophthalmology department of our hospital between June 2009 and March 2011, who were diagnosed with DR. A retrospective analysis were made on the clinical data of ECG, triglyceride, cholesterol and glycosylated hemoglobin. RESULTS:ST segment and T-wave abnormalities in ECGs were the major abnormalities. 25 cases (61.0%) in non-proliferative DR and 59 cases (81.9%) in proliferative DR had ECG abnormality. The difference was significant. Cases percentage in proliferation stage of DR patients with abnormal ECG was significantly higher than those of normal ECG group. Compared with normal ECG group, abnormal ECG group is also associated with higher average glycosylated hemoglobin. The difference was statistically significant (P<0.01). The difference of triglyceride and cholesterol levels between abnormal and normal ECG groups was not significant. CONCLUSION:As a severe complication in eyes, DR is associated with cardiovascular system diseases and the poor glycemia control.