目的:研究单纯玻璃酸钠滴眼液,及其联合鱼腥草滴眼液治疗干眼症的临床疗效。方法:选取确诊的干眼症患者125例198眼,随机分为单纯玻璃酸钠滴眼液组(A组)63例100眼和玻璃酸钠滴眼液联合鱼腥草滴眼液组(B组)62例98眼。A组用1g/L玻璃酸钠滴眼液治疗;B组交替给予1g/L玻璃酸钠滴眼液和鱼腥草滴眼液治疗。连续治疗2mo后,比较两组治疗前后的临床症状、泪液基础分泌试验(SⅠt)、泪膜破裂时间(BUT)及角膜荧光素染色(FL)程度。结果:两种治疗方法均可明显改善干眼症患者的临床症状、SⅠt,BUT和FL程度;但B组的主观症状、SⅠt,BUT和FL的改善程度明显优于A组。结论:玻璃酸钠滴眼液联合鱼腥草滴眼液可明显改善干眼症患者的临床症状,提高疗效。

AIM:To observe the effect of hyaluronate(HA)eye drops and HA eye drops combined with houttuynia cordata(HC)eye drops on the treatment of dry eye.METHODS:A total of 125 patients 198 eyes with dry eyes were randomly divided into group HA eye drops(group A)(63 cases,100 eyes)and group HA eye drops combined with HC eye drops(group B)(62 cases,98 eyes).The patients were treated with 1g/L HA eye drops in group A and 1g/L HA eye drops combined with HC eye drops in group B.After 2 months’ treatment,clinic symptom,Shirmer I test(S Ⅰ t),break-up time of tear film(BUT),and fluorescence staining(FL)were measured respectively.RESULTS:Both of the two methods could improve the clinic symptom,SⅠ t,BUT,and FL in group B were obviously better than those in group A.CONCLUSION:HA eye drops combined with HC eye drops can improve clinic symptoms of dry eye and heighten the effect of treatment.

R777