角膜生物参数对青光眼患者眼压测量影响的研究

Influence of corneal biomechanical properties on intraocular pressure measurements of the glaucoma patients

摘要:

目的:探讨角膜生物参数对青光眼患者眼压测量的影响。方法:对80例121眼青光眼患者进行眼反应分析仪(ocular response analyzer,ORA)与Goldmann压平眼压计(Goldmann applanation tonometer,GAT)测量,并用先进的OrbscanⅡ眼前节分析系统测量中央角膜厚度(central corneal thickness,CCT)。结果:平均矫正眼压(IOPcc)值17.41±5.62mmHg;平均GAT值15.76±6.06mmHg;IOPcc与角膜滞后性(cornealhysteresis,CH)有相关性(P=0.000;r=-0.236);IOPcc与GAT显著相关(P=0.000;r=0.857);IOPcc与CCT无相关性。结论:对已经诊断的青光眼患者,平均IOPcc值高于平均GAT值;随着CH的降低,IOPcc值有升高的趋势;且IOPcc值不受CCT值的影响。

Abstract:

AIM:To evaluate the influence of corneal biomechanical properties on intraocular pressure(IOP)measurements of the glaucoma patients.METHODS:The study included 121 eyes of 80 cases.All cases underwent IOP evaluation with the ocular response analyzer(ORA)and Goldmann applanation tonometry(GAT),and central corneal thickness(CCT)was measured with Orbscan Ⅱ.RESULTS:The mean IOPcc was 17.41±5.62mmHg;the mean GAT was 15.76±6.06mmHg.IOPcc was significantly associated with corneal hysteresis(CH)and GAT(P=0.000);IOPcc was not associated with CCT.CONCLUSION:For glaucoma patients,the mean IOPcc is higher than the mean GAT.The IOPcc tends to be higher,while the CH is lower.The IOPcc is not influenced by CCT.