目的:探讨更昔洛韦眼用凝胶和更昔洛韦滴眼液治疗带状疱疹角膜炎的疗效比较。方法:将68例68眼带状疱疹角膜炎患者随机分为更昔洛韦凝胶组(观察组)36例,更昔洛韦滴眼液(对照组)32例,两组患者均给予滴眼6次/d,并全身抗病毒综合治疗。结果:更昔洛韦凝胶组和滴眼液组之间总有效率无明显差异(P>0.05),但在病情痊愈时间上,凝胶组要短于滴眼液组,结果有统计学差异(P<0.05)。结论:更昔洛韦眼用凝胶与滴眼液治疗带状疱疹角膜炎在疗效上无明显差异,但是更昔洛韦凝胶能明显缩短病程。

AIM:To compare the clinical effect of ganciclovir ophthalmic gel and ganciclovir eye drops in the treatment of herpes zoster keratitis.METHODS:A total of 68 patients 68 eyes of herpes zoster keratitis were selected and divided into two groups randomly,there were 36 patients 36 eyes in ganciclovir ophthalmic gel group(observation group),32 patients 32 eyes in ganciclovir eye drops group(control group).All patients were used ganciclovir ophthalmic gel or ganciclovir eye drops six times per day,and they underwent systemic anti-viral treatment.RESULTS:The therapeutic efficiency between the observation group and the control group had no statistical difference(P>0.05).But the time of recovery in the observation group was less than that in the control group.The difference was statistically significant(P<0.05).CONCLUSION:The application of ganciclovir ophthalmic gel and ganciclovir dye drops in the treatment of herpes zoster keratitis has the same efficiency,but ganciclovir ophthalmic gel can shorten the time of recovery.