目的:评价玻璃体切除联合曲安奈德(triamcinolone acetonide,TA)球内注射治疗增生性糖尿病视网膜病变(proliferative diabetic refinopathy,PDR)的疗效。方法:分析本院因PDR住院治疗患者90例98眼,玻璃体切除术联合TA球内注射50眼和单纯行玻璃体切除术48眼,比较两组患者治疗前后的矫正视力、眼内炎症、反应眼压和眼底等情况。结果:随访至术后6mo。TA注射组术后前房炎症反应及黄斑水肿的发生率较单纯手术组降低,其差异有统计学意义(P<0.05),术后视力改善程度及眼压升高的发生率组间差异无统计学意义。结论:玻璃体切除联合TA球内注射治疗PDR与单纯玻璃体切除术比较,可以减少术后眼内炎症反应及黄斑水肿的发生。

AIM:To explore the clinical effect of pars plana vitrectomy(PPV)combined triamcinolone acetonide (TA) intravitreal injection for proliferative diabetic retinopathy (PDR).·METHODS:The study included 90 patients with PDR was who underwent PPV:TA group included 50 eyes,control group included 48 eyes. The visual acuity,inflammation,intraocular pressure and fundus were evaluated after surgery.·RESULTS:In the postoperative month 6,the inflammation reaction of anterior chamber and macular edema in TA group was less than that in control group (P<0.05).But the corrected visual acuity and intraocular pressure showed no shown statistical significance.·CONCLUSION:PPV combined TA intravitreal injection for PDR is useful to reduce postoperative intraocular inflammation and macular edema.

R779.6

中国川北医学院苗圃基金资助项目[苗圃(08)临-16]~~