目的:观察分析VKH综合征临床病例早期诊断与治疗中的问题。方法:收集、分析VKH综合征临床病例25例50眼,分别行眼科常规及FFA和OCT检查,分析其原因和鉴别诊断方法,大部分病例可获得早期正确诊断,也有少数病例曾被诊断为中心性浆液性脉络膜视网膜炎(4例)、青光眼(2例)、视神经视网膜炎(5例)等;所有确诊病例均给予大剂量糖皮质激素治疗,治疗2wk后复查眼部OCT。结果:所有患者经及时诊断与大剂量糖皮质激素治疗1 wk后,78%患眼视力恢复至>0.5。结论:FFA和OCT是目前早期鉴别诊断VKH综合征的有效方法,早期正确诊断和大剂量糖皮质激素治疗是VKH综合征良好预后的重要影响因素。

AIM:To analyse the problems in the early diagnosis and treatment of clinical cases with Vogt-Koyanagi-Harada (VKH) syndrome. METHODS:Twenty-five cases 50 eyes with VKH syndrome were collected and analysed,routine examination of FFA and OCT were performed,its reason and differential diagnosis method were analyzed,most of them were diagnosed correctly,some of them were diagnosed as central serous chorioretinopathy(4 cases),glaucoma(2 cases),optic neurve-retinitis(5 cases).All the cases were given high dose corticosteroise treatment,and examined with OCT after two weeks. RESULTS:After one week,all the patients’ visions recovered to better than 0.5 in 78%of eyes. CONCLUSION:FFA and OCT are the useful methods on early differential diagnosis of the VKH syndrome.Early correct diagnosis for VKH syndrome and high dose corticosteroise treatment are the important factors for the better prognosis.

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