目的:报告2例以视力下降为首发症状的白血病患者,采用光学相干断层扫描(OCT)识别和定位视网膜病变。方法:回顾性干涉个案报告。结果:伴随视力下降,确诊急性淋巴细胞白血病和慢性淋巴细胞白血病患者各1例。OCT发现1例为黄斑部浆液性脱离。另1例为视网膜低荧光浸润,OCT表现为高反射性损伤。在随访时间内,肿瘤完全缓解后视网膜改变消失,视力明显恢复。结论:OCT是一种检测、定位和跟踪的眼部肿瘤有价值的,非侵入性的诊断工具。

AIM:To report two cases whose decreased visual acuity was the first symptom of leukaemia and optical coherence tomography(OCT) allowed identification and localization of the retinal lesions. METHODS:Retrospective,interventional,case reports. RESULTS:One case of lymphoblastic acute leukaemia and chronic lymphoid leukaemia were diagnosed following decreased visual acuity.OCT showed macular serous detachment in the first case.The second case presented hypo fluorescent retinal infiltrates which appeared as hyper reflective lesions by OCT.Retinal changes disappeared and visual acuity was recovered following complete remission of the neoplasm. CONCLUSION:OCT is a valuable,non invasive diagnostic tool permitting detection,localization and follow-up of ocular dissemination of neoplasms.