光学相干断层成像与视野检查在早期青光眼诊断中的应用

Application of optical coherence tomography and standard automatic permetry in the early glaucoma

摘要:

目的:探讨光学相干断层成像(optical coherence tomo-graphy,OCT)自动视野检查法(standard automatic perme-try,SAP)在早期青光眼诊断中的应用。方法:青光眼患者42例68眼,双眼50眼,单眼18眼,男29例48眼,女13例20眼,左32眼,右36眼,其中开角型青光眼18眼,闭角型青光眼50眼,年龄为36～82(平均60.8±9.2)岁。应用自动视野检查法和光学相干断层扫描仪检查视盘C/D及视网膜神经纤维层的厚度。结果:自动视野检查和光学相干断层扫描(OCT)两种检测方法的阳性率分别为84.37%,93.75%,特别是对于开角型青光眼患者的早期诊断OCT的阳性率更明显。结论:青光眼患者视网膜神经纤维层的丧失或(和)变薄早于视野缺损;视野和OCT的联合应用对青光眼视野缺损进行定性、定量客观评诂。

Abstract:

AIM:To investigate the diagnonsis effect of optical coherence tomography (OCT),standard automatic permetry (SAP) in the early glaucoma. ·METHODS:Forty-two patients 68 eyes with glaucoma (binoculus/ ocellanae:25/18,male/female:29/13,left/right:32/36,open/close:18/50) aged 36-82 years old,the average age was 60.8±0.92. Visual disks C/D and retinal nerve fibers layer thickness were inspected by automatic vision inspection and OCT scanners. ·RESULTS:The positive rate of diagnonsis of automatic vision inspection and OCT was 84.37% and 93.75%,respectively. The positive rate of inspection in OCT was higher than that of automatic vision inspection for early glaucoma patients. ·CONCLUSION:For glaucoma patient,the loss of retinal nerve fibers is earlier than the change in field of vision defects. Combined of visual field and OCT method can qualitatively and quantitatively get an objective assessment for vision defects of glaucoma.