目的:观察自体角膜缘干细胞移植术治疗原发性翼状胬肉疗效。方法:把76例93眼原发性翼状胬肉患者随机分为两组:治疗组(41例51眼)行翼状胬肉切除联合自体角膜缘干细胞移植术;对照组(35例42眼)行翼状胬肉单纯切除术。胬肉复发的定义:血管纤维组织重新侵入角膜。结果:术后随访9～24mo。治疗组治愈率96%,复发率4%;对照组治愈率76%,复发率24%。两组复发率有统计学意义(χ2=8.09,P<0.01),两组均无明显并发症。结论:自体角膜缘干细胞移植术治疗原发性翼状胬肉疗效好,复发率低于单纯切除术。

AIM:To investigate the efficiency of limbal stem cells autografting technique in primary pterygium surgery.METHODS:Forty-one patients(51 eyes) with primary pterygium were treated by limbal stem cells autografting technique and 35 patients(42 eyes) with primary pterygium were treated by simple excision technique.The definition of recurrence was pterygium tissue over the limbus onto the cornea in the area of previous pterygium excision.RESULTS:The follow-up periods ranged from 9 to 24 months.In the therapeutic group,the cure rate was 96% and the recurrence rate was 4%,but in the control group the cure rate was 76% and the recurrence rate was 24%.There was a statistically significant difference in the recurrence rate between the patients who underwent simple excision and those who underwent limbal conjunctival autografting(χ 2=8.09,P<0.01).CONCLUSION:Limbal stem cells autografting is an effective surgical technique for the treatment of primary pterygium.It has a low recurrence rate when compared with the simple excision technique.

R779.6