目的:丝裂霉素C(mitomycin C,MMC)在LASEK术中应用对眼压的影响及轮廓动态眼压计在LASEK术中的应用。方法:在术前和术后1,4,12wk,分别采用轮廓动态眼压计(dynamic contour tonometer,DCT)测量接受LASEK治疗的对照组和MMC组近视患者各150眼的眼内压。结果:术前MMC组和对照组DCT眼压值分别为17.17±2.35,18.12±2.41mmHg。术后1,4,12wkMMC组和对照组DCT眼压值分别为17.09±2.72,17.24±2.39,17.12±2.67,17.52±2.47,18.01±2.69,17.66±2.54mmHg。手术前、后眼压差异无统计学意义。对照组和MMC组术前和术后1,4,12wkDCT眼压值,差异均无统计学意义。结论:DCT测量眼压可能更适合于曾经接受角膜屈光手术眼的眼压测量。通过DCT监测手术前、后眼压,丝裂霉素C对LASEK术后眼压无明显影响。

AIM:To evaluate the performance of dynamic contour tonometer(DCT)before and after LASEK surgery by applying mitomycin C.METHODS:Three hundred eyes of 150 myopic patients admitted in our hospital were included in this study.The left and right of eyes of 150 patients was randomly divided into two groups,0.2g/L MMC sponge was put onto the cornea ablation area in 2 minutes during the operation in 150 eyes of MMC group;BSS sponge was put onto the cornea ablation area in 2 minutes during the operation in 150 eyes of the control group.The IOP was measured with DCT before operation and 1 week and 4,12 weeks after operation.RESULTS:The IOP in MMC group and control group was 17.17±2.35mmHg,18.12±2.41mmHg before opera-tion respectively.The IOP in MMC group and control group was 17.09±2.72mmHg,17.24±2.39mmHg,17.12±2.67mmHg,17.52±2.47mmHg,18.01±2.69mmHg,17.66±2.54mmHg 1 week and 4,12 weeks after the operation respectively.There was no difference of DCT in the control group and MMC group at various time point after the operation respectively.CONCLUSION:DCT may be suitable for monitoring IOP in eyes that have had corneal refractive surgery.The application of MMC in LASEK has no effect on the IOP.

R779.63