目的:观察博士伦Zyoptix节约角膜个体化LASIK治疗近视的临床效果,同时分析术后高阶像差的变化。方法:因角膜相对较薄不适宜接受常规LASIK手术,而采用Zyoptix节约角膜个体化LASIK治疗的患者32例64眼,分析节约角膜的程度、术后1a余视力的恢复和6mm瞳孔直径下高阶像差的变化。结果:手术平均节约角膜组织29.27μm,节约组织达21.36%;术后1a余,裸眼视力为0.93±0.24,较术前裸眼视力显著提高(P<0.01),与术前最佳矫正视力0.96±0.09相似,比较无统计学差异;81%的眼裸眼视力≥术前最佳矫正视力,无1眼最佳矫正视力下降。在6mm瞳孔直径下,总体高阶像差、三阶彗差、四阶球差较术前分别增大1.76倍、2.10倍、3.90倍,与常规LASIK术相似。结论:Zyoptix节约角膜个体化LASIK可以节约角膜组织20%～25%,扩大近视治疗度数范围,临床上有良好的安全性、有效性和预测性。

AIM:To observe the Bausch & Lomb Zyoptix individualized LASIK of cornea saving treatment for myopia,and analyze postoperative changes in higher-order aberrations.METHODS:Thirty-two patients 64 eyes with thin cornea myopia unsuitable for conventional LASIK surgery under-went the Zyoptix LASIK surgery.The degree of the cornea saved,the recovery of vision at 1 year and 6mm pupil diameters changes in higher-order aberrations were analyzed.RESULTS:The average saved corneal tissue was 29.27μm (21.36%);1 year after operation,uncorrected visual acuity was 0.93±0.24,visual acuity was signifi-cantly improved compared with that of preoperative (P<0.01),and similar to the preoperative best-corrected visual acuity (0.96±0.09);81% of cases have the better postoperative visual acuity than the preoperative best-corrected visual acuity,visual acuity was improved in all cases.At 6mm pupil diameter,the overall higher-order aberrations,third order coma and the fourth order spherical aberration were increased 1.76 times,2.10 times,3.90 times compared with that of the preoperative,similar to conventional LASIK surgery.CONCLUSION:Zyoptix individualized LASIK of cornea saving can save 20%-25% of the corneal tissue,expand the treatment scope of myopia,and have a good safety,efficacy and predictability in clinic.

R779.63