目的:观察羊膜移植治疗大泡性角膜病变的临床疗效,探讨大泡性角膜病变有效可行的治疗方法。方法:回顾分析经羊膜移植进行治疗的18例18眼大泡性角膜病变,对18例患者术后眼部刺激症状消失时间、大泡消失例数、羊膜溶解时间、角膜上皮完全修复时间、视力改善状况进行分析评价。结果:大泡性角膜病变患者18例中,10例在术后3d内疼痛消失,18例大泡消失,15d内移植的新鲜羊膜全部溶解,无1例出现排斥反应,15d内角膜上皮完全修复。结论:羊膜移植治疗大泡性角膜病变是取材方便、费用低廉、效果可靠的治疗方法。

AIM:To observe the clinical efficacy of amniotic membrane transplantation for bullous keratopathy(BK) and investigate an effective and feasible treatment for BK. METHODS: Retrospective study of 18 cases with BK treated by amniotic membrane transplantation was conducted,the elapse time of the stimulation symptom of the eyes, the number of the bubbles vanised, the time of amnion dissolving, the time of corneal epithelium completely repair and the vision improvement were evaluated.RESULTS: Of the 18 cases, 10 cases got rid of pain in 3 days after the operation, 18 cases with the vanish of the bubbles, all cases with the amnion dissolved completely in 15 days, no cases had complication of rejection, all the cases with the corneal epithelium completely repaired in 15 days.CONCLUSION: Amniotic membrane transplantation is an effective and reliable treatment for BK with easily obtained and inexpensive materials.

R779.6