普拉洛芬联合人工泪液在干眼症中的应用

Combined pranoprofen and artificial tears on the treatment of dry eye syndrome

摘要:

目的:探讨抗炎治疗对于干眼症的临床意义。方法:回顾性分析2008-05/2009-05我院确诊的80例干眼症患者,随机分为人工泪液组(A组)及人工泪液+普拉洛芬组(B组),用药2wk后对比分析调查症状,检测BUT,角膜染色。结果:A组和B组在用药治疗后BUT及角膜病变程度测定两项检查结果比较,差异有统计学意义。B组在改善患者泪膜破裂时间及角膜染色明显优于A组。结论:人工泪液联合应用普拉洛芬,对于伴有眼部刺激症状的干眼症患者具有重要的临床应用价值。

Abstract:

AIM:To investigate the clinical significance of anti-inflammatory therapy for dry eye syndrome. METHODS: Eighty patients with dry eye syndrome were analyzed retrospectively and divided into the artificial tears group(group A) and combined artificial tears with pranoprofen group(group B). Break-up(BUT) and corneal staining were analyzed two weeks later. RESULTS:There were significant differences in BUT and corneal staining between the two groups after treatment. The combined treatment was better than artificial tears alone in lengthening the BUT of tear film and improving corneal staining. CONCLUSION: The combined therapy of pranoprofen and artificial tears possesses important clinical application value for the patients with dry eye syndrome accompanying irritation.