羊膜联合Ahmed青光眼减压阀植入术治疗新生血管性青光眼的疗效

Observation on the effect of biological amnion combined with Ahmed glaucoma valve implantation on neovascular glaucoma

摘要:

目的:观察羊膜联合Ahmed青光眼减压阀植入术在治疗新生血管性青光眼的疗效和并发症。方法:2008-01/2009-09行羊膜联合Ahmed青光眼减压阀植入术25例25眼和单纯Ahmed青光眼减压阀植入术23例23眼的年龄和病因基本匹配的两组患者进行回顾性比较分析。结果:羊膜联合Ahmed青光眼减压阀植入术组出院时成功率96%,术后3mo成功率88%,术后12mo成功率83%。单纯Ahmed青光眼减压阀植入术组出院时成功率91%,术后3mo成功率59%,术后12mo成功率55%。两组中远期效果比较经过χ2检验差异有统计学意义(P<0.05)。结论:羊膜联合Ahmed青光眼减压阀植入术能较安全、有效的治疗新生血管性青光眼,特别是在中远期疗效上优于单纯减压阀植入术。

Abstract:

AIM: To observe the long-term effect and complication of biological amnion combined with Ahmed glaucoma valve implanta-tion on neovascular glaucoma. METHODS: This was a retrospective observational case series. Patients with neovascular glaucoma underwent either of the two procedures from Jan. 2008 Sept. 2009. Twenty-five cases 25 eyes underwent biological amnion combined with Ahmed glaucoma valve implan-tation,while twenty-three cases 23 eyes underwent Ahmed glaucoma valve implantation. RESULTS: The success rate of biological amnion combined with Ahmed glaucoma valve implantation was 96% at the time of discharge from hospital and 88% 3 months later, 83% 12 months later; while the rate of Ahmed glaucoma valve implantation were 91% at the time of discharge from hospital and 59% 3 months later, 55% 12 months later. The long-term effects of the two groups had statistical difference (P<0.05). CONCLUSION: It is considered the biological amnion combined with Ahmed glaucoma valve implantation surgery may be effective and safe for treating neovascular glaucoma .