目的:观察Avastin联合曲安奈德玻璃体腔注射治疗糖尿病视网膜病变(diabetic retinopathy,DR)伴黄斑水肿(macularedema,ME)的临床效果。方法:选取2007-03/2008-04我院门诊或住院的DR伴ME患者34例,每例均为双眼发病,随机分为观察组17例,对照组17例,观察组采用玻璃体腔Avastin(20g/L)、曲安奈德(40g/L)联合注射治疗,对照组采用玻璃体腔曲安奈德(40g/L)注射治疗。观察并记录视力、眼压、视网膜新生血管和ME情况。结果:观察组的治愈率为64.7%,而对照组的治愈率仅为41.2%,观察组治愈率明显优于对照组(P<0.05)。结论:Avastin联合曲安奈德玻璃体腔注射治疗糖尿病视网膜病变伴黄斑水肿的有效的方法。

·AIM:To observe clinical effects of Avastin combined with vitreous cavity injection of triamcinolone acetonide in treatment of diabetic retinopathy(DR)with macular edema(ME).·METHODS:Thirty-four cases of the DR with ME inpatients or outpatients in our hospital from March 2007 to April 2008,with both eyes involved in each case,were randomly divided into observation group of 17 cases and control group of 17 cases.Observation group were treated with intravitreal Avastin(20g/L),triamcinolone acetonide(40g/L)co-injection and the control group received intravitreal triamcinolone acetonide(40g/L)injection.The visual acuity,intraocular pressure,retinal neovascularization and the ME situation were observed and recorded.·RESULTS:The cure rate of the observation group was 64.7%,while the cure rate of the control group was only 41.2%.Observation group was significantly better than control group in the cure rate(P<0.05).·CONCLUSION:Avastin combined with vitreous cavity injection of triamcinolone acetonide in treatment of DR with ME is an effective approach.·

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